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Prof. Dr. med. Alexandar Tzankov

 
 

Prof. Dr. med. Alexandar Tzankov
Histopathology and Autopsy
Medical Genetics and Pathology
University Hospital Basel
Schoenbeinstrasse 40
CH-4031 Basel

 
E-mail alexandar.tzankov@usb.ch
Tel. +41 61 265 3229
Fax +41 61 265 3194
 
Homepage
 
 

Alexandar Tzankov is the Head of Histopathology and Autopsy at the Institute of Genetics and Pathology of the University Hospital Basel. His areas of interests are:

- Genetic profiling of Hodgkin- and Reed-Sternberg cells of classical Hodgkin lymphoma enriched from archival formalin-fixed and paraffin-embedded tissue;

- Deep sequencing of nodal marginal zone B-cell lymphomas: diagnostic and theranostic perspectives;

- Tracing hematolymphoid tumor ancestry;

- Rapid translation of basic research findings to routine diagnostic applications.

For additional details, see http://www.unispital-basel.ch/en/das-universitaetsspital/bereiche/medizinische-querschnittsfunktionen/kliniken-institute-abteilungen/pathologie/research/news/
- Most important recent publications + reviews, related to stem cell research

 
Recent publications related to stem cell research:

  • Juskevicius D, Jucker D, Klingbiel D, Mamot C, Dirnhofer S, Tzankov A (2017). Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B-cell lymphoma: Mutational analysis of the SAKK 38/07 prospective clinical trial cohort. Journal of Hematology & Oncology 10:70.
     
  • Juskevicius D, Lorber T, Gsponer J, Perrina V, Ruiz C, Stenner-Liewen F, Dirnhofer S, Tzankov A (2016). Distinct genetic evolution patterns of relapsing diffuse large B-cell lymphoma revealed by genome wide copy number aberration and targeted sequencing analysis. Leukemia 30:2385-2395.
     
  • Stavropoulou V, Kaspar S, Brault L, Sanders MA, Juge S, Morettini S, Tzankov A, Iacovino M, Lau IJ, Milne TA, Royo H, Kyba M, Valk PJM, Peters AHFM, Schwaller J (2016): MLL-AF9 expression in hematopoietic stem cells drives a highly invasive AML expressing EMT-related genes linked to poor outcome. Cancer Cell 30:43-58.
     
  • Medinger M, Krenger W, Jakab A, Bucher C, Passweg J, Tzankov A (2015). Numerical impairment of nestin+ bone marrow niches in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation for acute myelogenous leukemia. Bone Marrow Transplantation 50:1453-1458.
     
  • Arranz L, Sánchez-Aguilera A, Martín-Pérez D, Isern J, Langa X, Tzankov A, Lundberg P, Schwaller J, Skoda RC, Méndez-Ferrer S (2014). Sympathetic neuropathy of blood stem cell niche is essential for myeloproliferative neoplasms. Nature 512:78-81.
     
  • Sterlacci W, Savic S, Fiegl M, Obermann E, Tzankov A (2014). Putative stem cell markers in non-small cell lung cancer – a clinicopathologic characterization. Journal of Thoracic Oncology 9:41-49.