Stem Cell Center of Competence ::: Uni Basel, Switzerland






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Prof. Markus Rüegg
Prof. Markus Rüegg

Biozentrum, University of Basel
Klingelbergstrasse 50/70
CH-4056 Basel / Switzerland
Phone +41 61 267 22 23
Fax +41 61 267 22 08


For additional details, see

Selected recent publications related to stem cells:

  • Martin SK, Fitter S, Dutta AK, Matthews MP, Walkley CR, Hall MN, Ruegg MA, Gronthos S, Zannettino AC. (2015). Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation. Stem Cells 33:1359-65.
  • Willmann R, Luca A, Nagaraju K, Rüegg MA. (2015). Best Practices and Standard Protocols as a Tool to Enhance Translation for Neuromuscular Disorders. J Neuromuscul Dis. 2:113-117.
  • Guridi M, Tintignac LA, Lin S, Kupr B, Castets P, Rüegg MA. (2015). Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21. Sci Signal. 8(402):ra113.
  • Guridi M, Kupr B, Romanino K, Lin S, Falcetta D, Tintignac L, Rüegg MA. (2016). Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism. Skelet Muscle 21;6:13.
  • Castets P, Frank S, Sinnreich M, Rüegg MA. (2016). Get the Balance Right": Pathological Significance of Autophagy Perturbation in Neuromuscular Disorders. J Neuromuscul Dis. 3:127-155.


  • Tintignac LA, Brenner HR, Rüegg MA. (2015). Mechanisms Regulating Neuromuscular Junction Development and Function and Causes of Muscle Wasting. Physiol Rev. 95(3):809-52.
  • Rion N, Rüegg MA. (2017). LncRNA-encoded peptides: More than translational noise? Cell Res. 27:604-605.
  • Reinhard JR, Lin S, McKee KK, Meinen S, Crosson SC, Sury M, Hobbs S, Maier G, Yurchenco PD, Rüegg MA. (2017). Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice. Sci Transl Med. 9(396).